Resveratrol

Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 1997 Jan 10;275(5297):218-20. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, IL 60612, USA.

Aziz MH, Reagan-Shaw S, Wu J, Longley BJ, Ahmad N. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? " FASEB J. 2005 Jul;19(9):1193-5. Epub 2005 Apr 18. Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.

Wu JM, Wang ZR, Hsieh TC, Bruder JL, Zou JG, Huang YZ. Mechanism of cardioprotection by resveratrol, a phenolic antioxidant present in red wine. Int J Mol Med. 2001 Jul;8(1):3-17. New York Medical College, Room 147, Department of Biochemistry and Molecular Biology, Basic Sciences Building, Valhalla, NY 10595, USA.

Zhuang H, Kim YS, Koehler RC, Dore S. Potential mechanism by which resveratrol, a red wine constituent, protects neurons. Ann N Y Acad Sci. 2003 May;993:276-86; discussion 287-8. Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA.

Juan ME, Vinardell MP, Planas JM. The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful. J Nutr. 2002 Feb;132(2):257-60. Departament de Fisiologia-Divisio IV, Facultat de Farmacia, Universitat de Barcelona, E-08028 Barcelona, Spain.

Adhami VM, Afaq F, Ahmad N. Suppression of ultraviolet B exposure-mediated activation of NF-kappaB in normal human keratinocytes by resveratrol. Neoplasia. 2003 Jan-Feb;5(1):74-82. Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.

Afaq F, Adhami VM, Ahmad N. Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicol Appl Pharmacol. 2003 Jan 1;186(1):28-37. Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.

Reagan-Shaw S, Afaq F, Aziz MH, Ahmad N. Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin. Oncogene. 2004 Jul 1;23(30):5151-60. Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.

Fu ZD, Cao Y, Wang KF, Xu SF, Han R. Chemopreventive effect of resveratrol to cancer. A Zheng. 2004 Aug;23(8):869-73. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, PR China.

Lin CB, Babiarz L, Liebel F, Roydon Price E, Kizoulis M, Gendimenico GJ, Fisher DE, Seiberg M. Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation. J Invest Dermatol. 2002 Dec;119(6):1330-40. Johnson & Johnson Skin Research Center, CPWW, Skillman, NJ 08558, USA.

Jang M, Pezzuto JM. Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin. Cancer Lett. 1998 Dec 11;134(1):81-9. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 60612, USA.

Lee SK, Mbwambo ZH, Chung H, Luyengi L, Gamez EJ, Mehta RG, Kinghorn AD, Pezzuto JM. Evaluation of the antioxidant potential of natural products. Comb Chem High Throughput Screen. 1998 Apr;1(1):35-46. Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago 60612, USA.

She QB, Bode AM, Ma WY, Chen NY, Dong Z. Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase. Cancer Res. 2001 Feb 15;61(4):1604-10. The Hormel Institute, University of Minnesota, Austin 55912, USA.

Kapadia GJ, Azuine MA, Tokuda H, Takasaki M, Mukainaka T, Konoshima T, Nishino H. Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis. Pharmacol Res. 2002 Jun;45(6):499-505. Laboratory of Natural Drug Products, Department of Pharmaceutical Sciences, School of Pharmacy, Howard University, 2300 4th Street NW, Washington, DC 20059, USA.

Bhat KP, Pezzuto JM. Cancer chemopreventive activity of resveratrol. Ann N Y Acad Sci. 2002 May;957:210-29. Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, and University of Illinois Cancer Center, University of Illinois at Chicago, Illinois 60612, USA.

Soleas GJ, Grass L, Josephy PD, Goldberg DM, Diamandis EP. A comparison of the anticarcinogenic properties of four red wine polyphenols. Clin Biochem. 2002 Mar;35(2):119-24. Quality Assurance Department, Liquor Control Board of Ontario, 55 Lakeshore Blvd. E., Toronto, Ontario M5E 1A4, Canada.

Bode AM, Dong Z. Signal transduction pathways: targets for chemoprevention of skin cancer. Lancet Oncol. 2000 Nov;1:181-8. Review. Hormel Institute, University of Minnesota, Austin 55912, USA.

Ding XZ, Adrian TE. Resveratrol inhibits proliferation and induces apoptosis in human pancreatic cancer cells. Pancreas. 2002 Nov;25(4):e71-6. Department of Surgery, Northwestern University Medical School, Chicago, Illinois, USA.

Delmas D, Rebe C, Lacour S, Filomenko R, Athias A, Gambert P, Cherkaoui-Malki M, Jannin B, Dubrez-Daloz L, Latruffe N, Solary E. Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells. J Biol Chem. 2003 Oct 17;278(42):41482-90. Epub 2003 Aug 05. INSERM U517, IFR100 Faculty of Medicine, 7 boulevard Jeanne d'Arc, 21000 Dijon, France.

Cuendet M, Pezzuto JM. The role of cyclooxygenase and lipoxygenase in cancer chemoprevention. Drug Metabol Drug Interact. 2000;17(1-4):109-57. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, and University of Illinois Cancer Center, University of Illinois at Chicago, 60612, USA.

Godichaud S, Krisa S, Couronne B, Dubuisson L, Merillon JM, Desmouliere A, Rosenbaum J. Deactivation of cultured human liver myofibroblasts by trans-resveratrol, a grapevine-derived polyphenol. Hepatology. 2000 Apr;31(4):922-31. Groupe de Recherches pour l'Etude du Foie INSERM E9917, Faculte des Sciences Pharmaceutiques, Universite Victor Segalen Bordeaux 2, Bordeaux, France.

Hsieh TC, Wu JM. Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines. Exp Cell Res. 1999 May 25;249(1):109-15. Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York 10595, USA.

Huang C, Ma WY, Goranson A, Dong Z. Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway. Carcinogenesis. 1999 Feb;20(2):237-42. The Hormel Institute, University of Minnesota, Austin 55912, USA.

Brito P, Almeida LM, Dinis TC. The interaction of resveratrol with ferrylmyoglobin and peroxynitrite; protection against LDL oxidation. Free Radic Res. 2002 Jun;36(6):621-31. Laboratorio de Bioquimica, Faculdade de Farmacia, Universidade de Coimbra and Centro de Neurociencias, Couraca dos Apostolos, 51, r/c, 3000-295 Coimbra, Portugal.

Das DK, Sato M, Ray PS, Maulik G, Engelman RM, Bertelli AA, Bertelli A. Cardioprotection of red wine: role of polyphenolic antioxidants. Drugs Exp Clin Res. 1999;25(2-3):115-20. Review. University of Connecticut School of Medicine, Farmington, CT 06030-1110, USA.

Haider UG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol Pharmacol. 2002 Oct;62(4):772-7. Department of Pharmacy, Center of Drug Research, University of Munich, Germany.

Murcia MA, Martinez-Tome M. Antioxidant activity of resveratrol compared with common food additives. J Food Prot. 2001 Mar;64(3):379-84. Department of Food Science, Veterinary Faculty, University of Murcia, Spain.

Huang SS, Tsai MC, Chih CL, Hung LM, Tsai SK. Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia. Life Sci. 2001 Jul 20;69(9):1057-65. Department of Pharmacology, College of Medicine, National Taiwan University, Taipei.

Jang JH, Surh YJ. Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radic Biol Med. 2003 Apr 15;34(8):1100-10. Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, South Korea.

Sun AY, Sun GY. Ethanol and oxidative mechanisms in the brain. J Biomed Sci. 2001 Jan-Feb;8(1):37-43. Department of Pharmacology, University of Missouri, Columbia, MO 65212, USA.

Cantos E, Garcia-Viguera C, de Pascual-Teresa S, Tomas-Barberan FA. Effect of postharvest ultraviolet irradiation on resveratrol and other phenolics of cv. Napoleon table grapes. J Agric Food Chem. 2000 Oct;48(10):4606-12. Laboratorio de Fitoquimica, Departamento de Ciencia y Tecnologia de Alimentos, CEBAS (CSIC), P.O. Box 4195, Murcia 30080, Spain.

Gupta YK, Briyal S, Chaudhary G. Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats. Pharmacol Biochem Behav. 2002 Jan-Feb;71(1-2):245-9. Department of Pharmacology, Neuropharmacology Laboratory, All India Institute of Medical Sciences, New Delhi 110029, India.

Docherty JJ, Smith JS, Fu MM, Stoner T, Booth T. Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice. Antiviral Res. 2004 Jan;61(1):19-26. Department of Microbiology/Immunology, Northeastern Ohio Universities, College of Medicine, PO Box 95, State Route 44, Rootstown, OH 44272, USA.

Chan MM. Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin. Biochem Pharmacol. 2002 Jan 15;63(2):99-104. Department of Microbiology and Immunology, Temple University School of Medicine, 3400 North Broad Street, Philadelphia, PA 19140, USA.

Jang JH, Surh YJ. Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells. Mutat Res. 2001 Sep 20;496(1-2):181-90. College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, 151-742, Seoul, South Korea.