Lecithin & PhosphatidylCholine

Schneider HG. Clinical experiences with a lecithin-containing oil for re-lubrication of the skin. Z Hautkr. 1979 Oct 1;54(19):849-52.

Schwarz JS, Weisspapir MR, Friedman DI. Enhanced transdermal delivery of diazepam by submicron emulsion (SME) creams. Pharm Res. 1995 May;12(5):687-92. Pharmos Ltd., Rehovot, Israel.

Krowczynski L, Stozek T. Liposomes as drug vehicles in percutaneous therapy. Pharmazie, 1984 Sep;39(9):627-9.

Jacobs M, Martin GP, Marriott C. Effects of phosphatidylcholine on the topical bioavailability of corticosteroids assessed by the human skin blanching assay. J Pharm Pharmacol. 1988 Dec;40(12):829-33. Department of Pharmacy, Brighton Polytechnic, UK.

Conte A, Ronca G, Petrini M, Mautone G. Effect of lecithin on epicutaneous absorption of diclofenac epolamine. Drugs Exp Clin Res. 2002;28(6):249-55. Department of Agricultural Sciences, University of Modena and Reggio Emilia, Reggio Emilia, Italy.

Katahira N, Murakami T, Kugai S, Yata N, Takano M. Enhancement of topical delivery of a lipophilic drug from charged multilamellar liposomes. J Drug Target. 1999;6(6):405-14. Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine, Japan.

Bentley MV, Marchetti JM, Ricardo N, Ali-Abi Z, Collett JH. Influence of lecithin on some physical chemical properties of poloxamer gels: rheological, microscopic and in vitro permeation studies. Int J Pharm. 1999 Dec 20;193(1):49-55. Department of Pharmaceutical Sciences, University of Sao Paulo, Avada do Cafe s/n, 14049-903, Ribeirao Preto, Brazil.

Sentjurc M, Vrhovnik K, Kristl J. Liposomes as a topical delivery system: the role of size on transport studied by the EPR imaging method. J Control Release. 1999 May 1;59(1):87-97. University of Ljubljana, Faculty of Pharmacy, Askerceva 7, 1000 Ljubljana, Slovenia.

Kirjavainen M, Monkkonen J, Saukkosaari M, Valjakka-Koskela R, Kiesvaara J, Urtti A. Phospholipids affect stratum corneum lipid bilayer fluidity and drug partitioning into the bilayers. J Control Release. 1999 Mar 29;58(2):207-14. Department of Pharmaceutics, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland.

Uchida Y, Ogawa T, Ohta M, Kondo M, Takada S, Yamamura M. Penetration of lysophosphatidylcholine into the dermis. J Dermatol. 1991 Sep;18(9):523-7. Cosmetics Laboratory, Kanebo, LTD., Kanagawa, Japan.

Wohlrab W, Lachmann U, Lasch J. Penetration of lecithin from hydrocortisone-containing liposomes into human skin. Dermatol Monatsschr. 1989;175(6):344-7.

Hsia SL, He JL, Nie Y, Fong K, Milikowski C. The hypocholesterolemic and antiatherogenic effects of topically applied phosphatidylcholine in rabbits with heritable hypercholesterolemia. Artery. 1996;22(1):1-23. Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Florida 33101, USA.