Clinical Resources

General References

Vayalil PK, Mittal A, Hara Y, Elmets CA, Katiyar SK. Green tea polyphenols prevent ultraviolet light-induced oxidative damage and matrix metalloproteinases expression in mouse skin. J Invest Dermatol. 2004 Jun;122(6):1480-7. Department of Dermatology, University of Alabama at Birmingham, Alabama 35294, USA.

Marini S, Fasciglione GF, Monteleone G, Maiotti M, Tarantino U, Coletta M. A correlation between knee cartilage degradation observed by arthroscopy and synovial proteinases activities. Clin Biochem. 2003 Jun;36(4):295-304. Department of Experimental Medicine and Biochemistry Science, University of Rome TorVergata, Rome, Italy.

Ahmad N, Gilliam AC, Katiyar SK, O'Brien TG, Mukhtar H. A definitive role of ornithine decarboxylase in photocarcinogenesis. Am J Pathol. 2001 Sep;159(3):885-92. Department of Dermatology, Case Western Reserve University and University Hospitals of Cleveland Ohio 44106, USA.

Hashimoto T, Wen G, Lawton MT, Boudreau NJ, Bollen AW, Yang GY, Barbaro NM, Higashida RT, Dowd CF, Halbach VV, Young WL; University of California, San Francisco BAVM Study Group. Abnormal expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in brain arteriovenous malformations. Stroke. 2003 Apr;34(4):925-31. Epub 2003 Mar 20. Department of Anesthesia and Perioperative Care, University of California, San Francisco 94110, USA.

Seite S, Zucchi H, Moyal D, Tison S, Compan D, Christiaens F, Gueniche A, Fourtanier A. Alterations in human epidermal Langerhans cells by ultraviolet radiation: quantitative and morphological study. Br J Dermatol. 2003 Feb;148(2):291-9. L'Oreal Recherche, Clichy, France.

Orbe J, Rodriguez JA, Arias R, Belzunce M, Nespereira B, Perez-Ilzarbe M, Roncal C, Paramo JA. Antioxidant vitamins increase the collagen content and reduce MMP-1 in a porcine model of atherosclerosis: implications for plaque stabilization. Atherosclerosis. 2003 Mar;167(1):45-53. Atherosclerosis Research Laboratory, Division of Cardiovascular Pathophysiology, School of Medicine, University of Navarra, C/Irunlarrea 1, CIFA, E-31008 Pamplona, Spain.

Jang M, Pezzuto JM. Cancer chemopreventive activity of resveratrol. Drugs Exp Clin Res. 1999;25(2-3):65-77. Department of Surgical Oncology, University of Illinois at Chicago, USA.

van der Laan WH, Quax PH, Seemayer CA, Huisman LG, Pieterman EJ, Grimbergen JM, Verheijen JH, Breedveld FC, Gay RE, Gay S, Huizinga TW, Pap T. Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3. Gene Ther. 2003 Feb;10(3):234-42. Division of Vascular and Connective Tissue Research, Gaubius Laboratory, TNO Prevention and Health, Leiden, Switzerland.

Circ Res. 2003 May 2;92(8):827-39. Kennedy Institute of Rheumatology Division, Faculty of Medicine, Imperial College London, 1 Aspenlea Rd, London W6 8LH, UK.

Lahav-Baratz S, Kraiem Z, Shiloh H, Koifman M, Ishai D, Dirnfeld M. Decreased expression of tissue inhibitor of matrix metalloproteinases in follicular fluid from women with polycystic ovaries compared with normally ovulating patients undergoing in vitro fertilization. Fertil Steril. 2003 Mar;79(3):567-71. Department of Obstetrics and Gynecology, IVF Unit, Carmel Medical Center, Haifa, Israel.

Hornebeck W. Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival. Pathol Biol (Paris). 2003 Dec;51(10):569-73.

Al Haj Zen A, Lafont A, Durand E, Brasselet C, Lemarchand P, Godeau G, Gogly B. Effect of adenovirus-mediated over expression of decorin on metalloproteinases, tissue inhibitors of metalloproteinases and cytokines secretion by human gingival fibroblasts. Matrix Biol. 2003 May;22(3):251-8. INSERM E-0016, Necker Medical School, 156, Rue de Vaugirard, 75015, Paris, France.

Kim SJ. Effect of biflavones of Ginkgo biloba against UVB-induced cytotoxicity in vitro. J Dermatol. 2001 Apr;28(4):193-9. Department of Dermatology, Chonnam National University Medical School, Kwangju 501-757, Korea.

Ditre CM, Griffin TD, Murphy GF, Sueki H, Telegan B, Johnson WC, Yu RJ, Van Scott EJ. Effects of alpha-hydroxy acids on photoaged skin: a pilot clinical, histologic, and ultrastructural study. J Am Acad Dermatol. 1996 Feb;34(2 Pt 1):187-95. Department of Dermatology, Hahnemann University School of Medicine, Philadelphia, Pennsylvania, USA.

Mayuga RD, Singer DH. Effects of intravenous amiodarone on electrical dispersion in normal and ischaemic tissues and on arrhythmia inducibility: monophasic action potential studies. Cardiovasc Res. 1992 Jun;26(6):571-9. Department of Medicine, Northwestern University Medical School, Chicago, IL 60611.

Yue H, Lee JD, Shimizu H, Uzui H, Mitsuke Y, Ueda T. Effects of magnesium on the production of extracellular matrix metalloproteinases in cultured rat vascular smooth muscle cells. Atherosclerosis. 2003 Feb;166(2):271-7. First Department of Internal Medicine, Fukui Medical University, 23-3 Shimoaizuki, Matsuoka-Cho, Fukui 910-1193, Japan.

Falk P, Ivarsson ML. Examination gloves affect secretion of matrix metalloproteinases and their inhibitors from human abdominal skin fibroblasts. Wound Repair Regen. 2003 May-Jun;11(3):230-4. Department of Surgery, Sahlgrenska University Hospital/Ostra, Goteborg University, Goteborg, Sweden.

Kirkegaard T, Hansen A, Bruun E, Brynskov J. Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease. Gut. 2004 May;53(5):701-9. Department of Medical Gastroenterology C, Herlev Hospital, University of Copenhagen, Denmark.

Holven KB, Halvorsen B, Schulz H, Aukrust P, Ose L, Nenseter MS. Expression of matrix metalloproteinase-9 in mononuclear cells of hyperhomocysteinaemic subjects. Eur J Clin Invest. 2003 Jul;33(7):555-60. Research Institute for Internal Medicine, Rikshospitalet University Hospital, 0027 Oslo, Norway.

Razzaque MS, Kumari S, Foster CS, Ahmed AR. Expression profiles of collagens, HSP47, TGF-beta1, MMPs and TIMPs in epidermolysis bullosa acquisita. Cytokine. 2003 Mar 7;21(5):207-13. Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA.

Kim MH. Flavonoids inhibit VEGF/bFGF-induced angiogenesis in vitro by inhibiting the matrix-degrading proteases. Cell Biochem. 2003 Jun 1;89(3):529-38. Department of Molecular Biology and Immunology and Institute for Cancer Research, University of North Texas Health Science Center, Fort Worth, Texas 76107-2699, USA.

Kuittinen O, Apaja-Sarkkinen M, Turpeenniemi-Hujanen T. Gelatinases (MMP-2 and MMP-9), TIMP-1 expression and the extent of neovascularization in aggressive non-Hodgkin's lymphomas. Eur J Haematol. 2003 Aug;71(2):91-9. Department of Oncology and Radiotherapy, Oulu University Hospital, Oulu, Finland.

Matsubara K. Genetic structure and regulation of a replicon of plasmid lambdadv. J Mol Biol. 1976 Apr 15;102(3):427-39.

Bernstein EF, Lee J, Brown DB, Yu R, Van Scott E. Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatol Surg. 2001 May;27(5):429-33. DakDak Photoaging Technologies, Wynnewood, Pennsylvania, Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Lanchou J, Corbel M, Tanguy M, Germain N, Boichot E, Theret N, Clement B, Lagente V, Malledant Y. Imbalance between matrix metalloproteinases (MMP-9 and MMP-2) and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in acute respiratory distress syndrome patients. Crit Care Med. 2003 Feb;31(2):536-42. INSERM U456, Universite de Rennes, Service de Reanimation Chirurgicale, CHU de Rennes, Hopital de Pontchaillou, France.

Schulze CJ, Wang W, Suarez-Pinzon WL, Sawicka J, Sawicki G, Schulz R. Imbalance between tissue inhibitor of metalloproteinase-4 and matrix metalloproteinases during acute myocardial [correction of myoctardial] ischemia-reperfusion injury. Circulation. 2003 May 20;107(19):2487-92. Epub 2003 Apr 21. Department of Pharmacology, University of Alberta, Edmonton, Alberta, T6G 2S2 Canada.

Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R. Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis. J Invest Dermatol. 2004 Feb;122(2):330-6. Department of Dermatology, University of California at San Francisco, and Veterans Affairs Medical Center, San Francisco, California 94121, USA.

Lorenzl S, Albers DS, Relkin N, Ngyuen T, Hilgenberg SL, Chirichigno J, Cudkowicz ME, Beal MF. Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease. Neurochem Int. 2003 Aug;43(3):191-6. Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 525 East 68th Street, Room F-610, New York, NY 10021, USA.

Ramos MC, Steinbrenner H, Stuhlmann D, Sies H, Brenneisen P. Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation. Biol Chem. 2004 Jan;385(1):75-86. Institute for Biochemistry and Molecular Biology I, Heinrich Heine University Dusseldorf, Universitatstrasse 1, D-40225 Dusseldorf, Germany.

Choe T, Lee B, Park I, Hong S. Inhibition of matrix metalloproteinase-1 and -2 expression using nitric oxide synthase inhibitors in UV-irradiated human dermal fibroblasts. J Cosmet Sci. 2003 May-Jun;54(3):229-38. Division of Chemical and Biological Engineering, Konkuk University, Hwayang-dong l, Kwangjin-gu, Seoul 143-701, Korea.

Gonzalez S, Pathak MA. Inhibition of ultraviolet-induced formation of reactive oxygen species, lipid peroxidation, erythema and skin photosensitization by polypodium leucotomos. Photodermatol Photoimmunol Photomed. 1996 Apr;12(2):45-56. Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.

Power C, Henry S, Del Bigio MR, Larsen PH, Corbett D, Imai Y, Yong VW, Peeling J. Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases. Ann Neurol. 2003 Jun;53(6):731-42. Department of Clinical Neurosciences, University of Calgary, Alberta, Canada.

Trabucchi E, Pallotta S, Morini M, Corsi F, Franceschini R, Casiraghi A, Pravettoni A, Foschi D, Li D, Liu L, Chen H, Sawamura T, Ranganathan S, Mehta JL. LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation. 2003 Feb 4;107(4):612-7. Department of Medicine, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock 72205, USA.

Kettlun A, Collados L, Garcia L, Cartier LA, Wolf ME, Mosnaim AD, Valenzuela MA. Matrix metalloproteinase profile in patients with Creuztfeldt-Jakob disease. Int J Clin Pract. 2003 Jul-Aug;57(6):475-8. Department of Biochemistry and Molecular Biology, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile.

Brennan M, Bhatti H, Nerusu KC, Bhagavathula N, Kang S, Fisher GJ, Varani J, Voorhees JJ. Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin. Photochem Photobiol. 2003 Jul;78(1):43-8. Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Li QL, Illman SA, Wang HM, Liu DL, Lohi J, Zhu C. Matrix metalloproteinase-28 transcript and protein are expressed in rhesus monkey placenta during early pregnancy. Mol Hum Reprod. 2003 Apr;9(4):205-11. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, 25 Beisihuan Xilu, Haidian District, Beijing 100080, PR China.

Yang YN, Bauer D, Wasmuth S, Steuhl KP, Heiligenhaus A. Matrix metalloproteinases (MMP-2 and 9) and tissue inhibitors of matrix metalloproteinases (TIMP-1 and 2) during the course of experimental necrotizing herpetic keratitis. Exp Eye Res. 2003 Aug;77(2):227-37. Department of Ophthalmology, Ophtha-Lab., St Franziskus Hospital, Munster, Germany.

Edwards JG, McLaren J, Jones JL, Waller DA, O'Byrne KJ. Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura. Br J Cancer. 2003 May 19;88(10):1553-9. University Department of Medical Oncology, Osborne Building, Leicester Royal Infirmary, Leicester LE1 5WW, UK.

Beaudeux JL, Giral P, Bruckert E, Foglietti MJ, Chapman MJ. Matrix metalloproteinases and atherosclerosis. Therapeutic aspects. Ann Biol Clin (Paris). 2003 Mar-Apr;61(2):147-58. Service de biochimie C, Group hospitalier Pitie-Salpetriere, AP-HP, 47-83 boulevard de l'hopital, 75651 Paris cedex 13.

Ikeda U, Shimada K. Matrix metalloproteinases and coronary artery diseases. Clin Cardiol. 2003 Feb;26(2):55-9. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical School, Tochigi, Japan.

Schlotzer-Schrehardt U, Lommatzsch J, Kuchle M, Konstas AG, Naumann GO. Matrix metalloproteinases and their inhibitors in aqueous humor of patients with pseudoexfoliation syndrome/glaucoma and primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1117-25. Department of Ophthalmology, University of Erlangen-Nurnberg, Erlangen, Germany.

Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res. 2003 May 2;92(8):827-39. Kennedy Institute of Rheumatology Division, Faculty of Medicine, Imperial College London, 1 Aspenlea Rd, London W6 8LH, UK.

Chavey C, Mari B, Monthouel MN, Bonnafous S, Anglard P, Van Obberghen E, Tartare-Deckert S. Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation. J Biol Chem. 2003 Apr 4;278(14):11888-96. Epub 2003 Jan 15. INSERM, Unite 145, Institut Federatif de Recherche (IFR) 50, 06107 Nice, France.

Tsuruda T, Costello-Boerrigter LC, Burnett JC Jr. Matrix metalloproteinases: pathways of induction by bioactive molecules. Heart Fail Rev. 2004 Jan;9(1):53-61. Cardiorenal Research Laboratory, Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Woodside KJ, Hu M, Burke A, Murakami M, Pounds LL, Killewich LA, Daller JA, Hunter GC. Morphologic characteristics of varicose veins: possible role of metalloproteinases. J Vasc Surg. 2003 Jul;38(1):162-9. Department of Surgery, University of Texas Medical Branch, Galveston, Texas 77555, USA.

Mukherjee R, Brinsa TA, Dowdy KB, Scott AA, Baskin JM, Deschamps AM, Lowry AS, Escobar GP, Lucas DG, Yarbrough WM, Zile MR, Spinale FG. Myocardial infarct expansion and matrix metalloproteinase inhibition. Circulation. 2003 Feb 4;107(4):618-25. Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.

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Schauder S, Ippen H. Photoallergic and allergic contact dermatitis from dibenzoylmethanes. Photodermatol. 1986 Jun;3(3):140-7.

Koskinen SO, Heinemeier KM, Olesen JL, Langberg H, Kjaer M. Physical exercise can influence local levels of matrix metalloproteinases and their inhibitors in tendon-related connective tissue. J Appl Physiol. 2004 Mar;96(3):861-4. Epub 2003 Sep 23. Sports Medicine Research Unit, Bispebjerg Hospital, Copenhagen, Denmark.

Philips N, Smith J, Keller T, Gonzalez S. Predominant effects of Polypodium leucotomos on membrane integrity, lipid peroxidation, and expression of elastin and matrixmetalloproteinase-1 in ultraviolet radiation exposed fibroblasts, and keratinocytes. J Dermatol Sci. 2003 Jun;32(1):1-9. Departments of Biology and Chemistry/Biochemistry, Georgian Court College, Lakewood, NJ, USA.

Baker EA, Leaper DJ. Profiles of matrix metalloproteinases and their tissue inhibitors in intraperitoneal drainage fluid: relationship to wound healing. Wound Repair Regen. 2003 Jul-Aug;11(4):268-74. Professional Unit of Surgery, University Hospital of North Tees, Stockton on Tees, United Kingdom.

Fehrenbacher A, Steck E, Rickert M, Roth W, Richter W. Rapid regulation of collagen but not metalloproteinase 1, 3, 13, 14 and tissue inhibitor of metalloproteinase 1, 2, 3 expression in response to mechanical loading of cartilage explants in vitro. Arch Biochem Biophys. 2003 Feb 1;410(1):39-47. Department of Orthopaedic Surgery, University of Heidelberg, Abteilung Bereich Forschung, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany.

Wilson EM, Moainie SL, Baskin JM, Lowry AS, Deschamps AM, Mukherjee R, Guy TS, St John-Sutton MG, Gorman JH 3rd, Edmunds LH Jr, Gorman RC, Spinale FG. Region- and type-specific induction of matrix metalloproteinases in post-myocardial infarction remodeling. Circulation. 2003 Jun 10;107(22):2857-63. Epub 2003 May 27. Medical University of South Carolina, Charleston, SC 29425, USA.

Ben-Shlomo I, Goldman S, Shalev E. Regulation of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of MMP, and progesterone secretion in luteinized granulosa cells from normally ovulating women with polycystic ovary disease. Fertil Steril. 2003 Mar;79 Suppl 1:694-701. Ha'Emek Medical Center, Department of Obstetrics and Gynecology, Afula, Israel.

Dang CM, Beanes SR, Lee H, Zhang X, Soo C, Ting K. Scarless fetal wounds are associated with an increased matrix metalloproteinase-to-tissue-derived inhibitor of metalloproteinase ratio. Plast Reconstr Surg. 2003 Jun;111(7):2273-85. Department of Surgery, School of Medicine, University of California, Los Angeles, 90095, USA.

Avolio C, Ruggieri M, Giuliani F, Liuzzi GM, Leante R, Riccio P, Livrea P, Trojano M. Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes. J Neuroimmunol. 2003 Mar;136(1-2):46-53. Neurology Unit, University of Foggia, Italy.

Oscar-Berman M, Sahakian BJ. Spatial probability learning by alcoholic Korsakoff patients. J Exp Psychol [Hum Learn]. 1976 Mar;2(2):215-22.

Garmyn M, Degreef H, Gilchrest BA. The effect of acute and chronic photodamage on gene expression in human keratinocytes. Dermatology. 1995;190(4):305-8. Department of Dermatology, UZ Sint Rafael, Catholic University of Leuven, Belgium.

Moon SE, Park SB, Ahn HT, Youn JI. The effect of glycolic acid on photoaged albino hairless mouse skin. Dermatol Surg. 1999 Mar;25(3):179-82. Department of Dermatology, Seoul National University College of Medicine, Korea.

Sudel KM, Venzke K, Knussmann-Hartig E, Moll I, Stab F, Wenck H, Wittern KP, Gercken G, Gallinat S. Tight control of matrix metalloproteinase-1 activity in human skin. Photochem Photobiol. 2003 Oct;78(4):355-60. Beiersdorf AG, Paul Gerson Unna Skin Research Center, Unnastr. 48, 20245 Hamburg, Germany.

Uric D, Noah EM, von Heimburg D, Pallua N. TIMP-1, MMP-2, MMP-9, and PIIINP as serum markers for skin fibrosis in patients following severe burn trauma. Plast Reconstr Surg. 2003 Apr 1;111(4):1423-31. Department of Plastic Surgery and Hand Surgery, Burn Center, University Hospital, Aachen University of Technology, Aachen, Germany.

Wilgus TA, Ross MS, Parrett ML, Oberyszyn TM. Topical application of a selective cyclooxygenase inhibitor suppresses UVB mediated cutaneous inflammation. Prostaglandins Other Lipid Mediat. 2000 Oct;62(4):367-84. Department of Molecular Virology, Immunology and Medical Genetics, College of Medicine, Ohio State University, Columbus 43210, USA.

Vassar R, Fuchs E. Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation. Genes Dev. 1991 May;5(5):714-27. Howard Hughes Medical Institute, Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637.

Nawrocki-Raby B, Gilles C, Polette M, Bruyneel E, Laronze JY, Bonnet N, Foidart JM, Mareel M, Birembaut P. Upregulation of MMPs by soluble E-cadherin in human lung tumor cells. Int J Cancer. 2003 Jul 20;105(6):790-5. INSERM UMRS 514, Laboratoire Pol Bouin, IFR 53, CHU Maison Blanche, Reims, France.

Steinbrenner H, Ramos MC, Stuhlmann D, Sies H, Brenneisen P. UVA-mediated downregulation of MMP-2 and MMP-9 in human epidermal keratinocytes. Biochem Biophys Res Commun. 2003 Aug 29;308(3):486-91. Institute for Biochemistry and Molecular Biology I, Heinrich-Heine-University Dusseldorf, Germany.