Ellagic Acid (Pomegranate Seed Extract)

Lee JH, Talcott ST. Fruit maturity and juice extraction influences ellagic acid derivatives and other antioxidant polyphenolics in muscadine grapes. J Agric Food Chem. 2004 Jan 28;52(2):361-6. Department of Food Science and Human Nutrition, Institute of Food and Agricultural Sciences, University of Florida, P.O. Box 110370, Gainesville, Florida 32611-0370, USA.

Pastrana-Bonilla E, Akoh CC, Sellappan S, Krewer G. Phenolic content and antioxidant capacity of muscadine grapes. J Agric Food Chem. 2003 Aug 27;51(18):5497-503. Department of Food Science and Technology, The University of Georgia, Athens, Georgia 30602-7610, USA.

Verotta L, Dell'Agli M, Giolito A, Guerrini M, Cabalion P, Bosisio E. In vitro antiplasmodial activity of extracts of Tristaniopsis species and identification of the active constituents: ellagic acid and 3,4,5-trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside . J Nat Prod. 2001 May;64(5):603-7. Department of Organic and Industrial Chemistry and Institute of Pharmacological Sciences, University of Milan, Italy.

Lesca P. Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice. Carcinogenesis. 1983 Dec;4(12):1651-3.

Ashoori F, Suzuki S, Zhou JH, Isshiki N, Miyachi Y. Involvement of lipid peroxidation in necrosis of skin flaps and its suppression by ellagic acid. Plast Reconstr Surg. 1994 Dec;94(7):1027-37. Department of Plastic and Reconstructive Surgery, Kyoto University Hospital, Japan.

Glaser KB, Sung ML, Hartman DA, Lock YW, Bauer J, Walter T, Carlson RP. Cellular and topical in vivo inflammatory murine models in the evaluation of inhibitors of phospholipase A2. Skin Pharmacol. 1995;8(6):300-8. Inflammatory Diseases, Wyeth-Ayerst Research, Princeton, N.J., USA.

Stoner GD, Mukhtar H. Polyphenols as cancer chemopreventive agents. J Cell Biochem Suppl. 1995;22:169-80. Department of Preventive Medicine, Ohio State University, Columbus 43210, USA.

Perchellet JP, Gali HU, Perchellet EM, Klish DS, Armbrust AD. Antitumor-promoting activities of tannic acid, ellagic acid, and several gallic acid derivatives in mouse skin. Basic Life Sci. 1992;59:783-801. Anti-Cancer Drug Laboratory, Kansas State University, Manhattan 66506-4901.

Chang RL, Huang MT, Wood AW, Wong CQ, Newmark HL, Yagi H, Sayer JM, Jerina DM, Conney AH. Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse. Carcinogenesis. 1985 Aug;6(8):1127-33.

Gali HU, Perchellet EM, Klish DS, Johnson JM, Perchellet JP. Hydrolyzable tannins: potent inhibitors of hydroperoxide production and tumor promotion in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate in vivo. Int J Cancer. 1992 May 28;51(3):425-32. Anti-Cancer Drug Laboratory, Kansas State University, Manhattan 66506.

Del Tito BJ Jr, Mukhtar H, Bickers DR. Inhibition of epidermal metabolism and DNA-binding of benzo[a]pyrene by ellagic acid. Biochem Biophys Res Commun. 1983 Jul 18;114(1):388-94.

Gali HU, Perchellet EM, Klish DS, Johnson JM, Perchellet JP. Antitumor-promoting activities of hydrolyzable tannins in mouse skin. Carcinogenesis. 1992 Apr;13(4):715-8. Division of Biology, Kansas State University, Manhattan 66506-4901.

Mukhtar H, Das M, Del Tito BJ Jr, Bickers DR. Protection against 3-methylcholanthrene-induced skin tumorigenesis in Balb/C mice by ellagic acid. Biochem Biophys Res Commun. 1984 Mar 15;119(2):751-7.

Mukhtar H, Das M, Del Tito BJ Jr, Bickers DR. Epidermal benzo[a]pyrene metabolism and DNA-binding in Balb/C mice: inhibition by ellagic acid. Xenobiotica. 1984 Jul;14(7):527-31.

Bickers DR, Das M, Mukhtar H. Pharmacological modification of epidermal detoxification systems. Br J Dermatol. 1986 Aug;115 Suppl 31:9-16.

Mukhtar H, Del Tito BJ Jr, Marcelo CL, Das M, Bickers DR. Ellagic acid: a potent naturally occurring inhibitor of benzo[a]pyrene metabolism and its subsequent glucuronidation, sulfation and covalent binding to DNA in cultured BALB/C mouse keratinocytes. Carcinogenesis. 1984 Dec;5(12):1565-71.

Tanaka T, Kojima T, Kawamori T, Wang A, Suzui M, Okamoto K, Mori H. Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis by the naturally occurring plant phenolics caffeic, ellagic, chlorogenic and ferulic acids. Carcinogenesis. 1993 Jul;14(7):1321-5. 1st Department of Pathology, Gifu University School of Medicine, Japan.